Appearance: White to off white solid Melting point: 60-63 °C (lit.) Boiling point: 132°C/0.4mmHg(lit.) Predicted Density: 1.37± 0.1g /cm3 Solubility: Chloroform, Ethyl Acetate Predicted Acidity coefficient (pKa): -2.19±0.29(Predicted) Morphology: SolidStorage Condition Store in a cool, dry, well-ventilated place, away from fire and heat sources. Mode of transport Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate can be transported by road, rail, water and air. International and local transport regulations, laws and regulations should be observed during transportation. Transport Condition During transportation, high temperature, sun exposure, humidity and mechanical collision should be avoided to avoid affecting product quality. The specific requirements for transporting Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate may vary from country to country and region. It is recommended to consult relevant transport professionals and follow relevant regulations before transporting. Package Packed in 25kg /50kg plastic drum, or packed according to customer needs.
TESTING ITEM
SPECIFICATION
Characteristics
White to off white solid
Water Content
≤0.5%
Purity(by HPLC)
≥98.0%
Assay(by HPLC)
≥98.0%
Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate is an organic synthesis intermediate and pharmaceutical intermediate, mainly used in the synthesis of avanafil important intermediate. Avanafil is an oral, fast-acting, highly selective phosphodiesterase-5 (PDE-5) inhibitor used to treat erectile dysfunction in men. Ethyl 4-chloro-2-methylthio-5-pyrimidinecarboxylate as organic synthesis intermediates and pharmaceutical intermediates, used in laboratory research and development process and chemical pharmaceutical synthesis process.Danger symbol (GHS): Warning word: Warning Hazard description: H315-H319-H335 Precautions: P261-P264-P271-P280-P302+P352-P305+P351+P338 Danger Class code: 36/37/38 Safety Instructions:26-36 WGK Germany: 3 Hazard Note :Irritant Danger level: IRRITANT, KEEP COLD HS Code: 29339900 4-(ethylaMino)-2-(Methylthio)pyriMidine-5-carbaldehyde,(4-Chloro-2-methylsulfanyl-pyrimidin-5-yl)methanol ,4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde